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Lifestyle

Taking little stress may be good for you: Study

Worried that being in stressful situations might harm you? Take heart. According to a study, taking a little stress can be good for your cells as it boosts resilience, protects ageing cells as well as delays the risk of disease.

The findings will help researchers better understand the molecular mechanisms that drive ageing and risk for age-associated degenerative diseases.

"Our findings offer us a strategy for looking at ageing in humans and how we might prevent or stabilise against cell decline as we age," said Richard I. Morimoto, Professor at the Northwestern University.

"Our goal is not trying to find ways to make people live longer but rather to increase health at the cellular and molecular levels, so that a person's span of good health matches their lifespan," Morimoto added.

For the study, published in the journal Cell Reports, the team screened a transparent roundworm C. elegans' approximately 22,000 genes.

The researchers found that signals from mildly stressed mitochondria -- the cellular source of energy -- prevent the failure of protein-folding quality control (proteostasis) machinery that comes with age.

This, in turn, suppresses the accumulation of damaged proteins that can occur in degenerative diseases, such as Alzheimer's, Huntington's and Parkinson's diseases and amyotrophic lateral sclerosis (ALS).

"People have always known that prolonged mitochondrial stress can be deleterious. But we discovered that when you stress mitochondria just a little, the mitochondrial stress signal is actually interpreted by the cell and animal as a survival strategy," Morimoto said.

"It makes the animals completely stress-resistant and doubles their lifespan. It's like magic," he added.

C.elegans has a biochemical environment and cellular properties similar to that of humans. The findings in the transparent roundworm may have implications for humans and quality of life.

(IANS)

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Passenger manhandling case: IndiGo breaks down tarmac terror; here’s what it has to say!

Passenger manhandling case: IndiGo breaks down tarmac terror; here’s what it has to say!

A day after being slammed for manhandling a passenger, IndiGo has presented its version of the entire incident. While the video shows the passenger was being manhandled by the IndiGo staff, the airline has added a new twist saying the apparent whistleblower, who shot the video, was the main culprit in the incident.

The airline made the revelation in its report which was submitted to the Ministry of Civil Aviation on Wednesday.Here’s how the incident unfolded according to IndiGo.

https://twitter.com/ANI/status/927915529163046912

 

On Tuesday, Union Minister Jayant Sinha sought a report from budget carrier IndiGo regarding the incident at Delhi airport last month, when a passenger was manhandled by the airline's staff.

The incident happened on October 15 surfaced only on Tuesday after a video showed passenger Rajiv Katyal being manhandled by the airline's staff after a verbal altercation. Katyal, who arrived from Chennai, was waiting for the passenger bus at the airport when the incident happened. It is not clear exactly who started the verbal altercation.

However, the airline, in its report, owned up to the fault and clarified that its employee Montu Kalra  (since sacked by IndiGo) who shot the video was indeed the one who instigated the incident.