According to Downdetector, which monitors the status of some of the most-heavily visited websites in the world, there were 17,273 reports of malfunctioning for Instagram at about 7:30pm UK time.
More than half (58%) had to do with the app while 23% related to server connection issues.
Facebook also appears to be down for some users as 765 reports were received by Downdetector.
WhatsApp and Instagram users could access the apps but were unable to see any new content, including any sent or received messages.
The latest Instagram issues come in the aftermath of a major outage at the start of this week which affected all Facebook-owned apps.
On Monday Facebook, Facebook Messenger, WhatsApp and Instagram all suffered huge outages that affected millions of users.
Users took to Twitter to complain about Facebook and Instagram down
A user tweeted: “Both times Instagram has gone down this week I spend all morning on it with no problem and as soon as I try to post something it won’t load”.
While another posted: “Whoever is head of household at @instagram and @Facebook pay your light bill”.
One added: “Instagram is down again bye”.
And another wrote: “Instagram don’t let me down pleeeaaaase”.
— Semidey (@Semidey15) October 8, 2021
— वि शा ल (@_iamvish) October 8, 2021
— Lewis (@Iewis20) October 8, 2021