The 19 people are accused of irregularities and negligence in the report submitted by a high-level inquiry committee set up by the state government to probe into the tragedy that took place in Hazratganj area on Monday.
A spokesperson said on Saturday that the chief minister gave the instructions after receiving the report of Lucknow Commissioner of Police SB Shiradkar and Divisional Commissioner Roshan Jacob.
The spokesman said departmental action, including suspension, will be taken against officials of the Departments of Home, Energy, Appointment and Personnel, Housing and Urban Planning and Excise.
The official said action will also be taken against those who retired according to prevailing rules.
Four people were killed and 10 others injured in the fire at Hotel Levana Suits on Monday. Police registered a case of culpable homicide not amounting to murder and attempt to murder against the hotel owners and the general manager. Three people have been arrested in the case so far.