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International M.P.S. Awareness Day 2023: Date, History and Facts

Mucopolysaccharidosis is a genetic lysosomal storage disease brought on by the inability of the organism to produce a particular enzyme.

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International M.P.S. Awareness Day 2023: Date, History and Facts

International M.P.S. Awareness Day 2023: May 15 is observed annually as International M.P.S. Awareness Day. This yearly event raises awareness of Mucopolysaccharidose (M.P.S.) Disorders. Each year, members of the MPS society strive to educate and raise awareness about the diagnosis, symptoms, and treatment of MPS. Mucopolysaccharidosis is a genetic lysosomal storage disease brought on by the inability of the organism to produce a particular enzyme. The lack of or insufficiency of the enzyme prevents cells from recycling debris, leading to the accumulation of substances in cells throughout the body. M.P.S. has over 40 inherited diseases caused by lysosome organelle dysfunction.


Mucopolysaccharidosis (M.P.S.) is a group of metabolic disorders caused by a deficiency of specific enzymes required to break down sugar carbohydrates that contribute to the formation of bone, skin, and connective tissue. Individuals with M.P.S. produce insufficient enzymes or enzymes that do not function adequately to break down these sugar chains into simpler molecules. This causes persistent cell damage and alters the physical appearance, organ function, and system functioning of the individual.

There are numerous types of M.P.S., and it is estimated that one in every 25,000 births is affected. In 1917, Dr. Charles Hunter identified M.P.S. Type II and provided the first description of the disorder. In 1919, Gertrude Hurler identified and described two cases similar to Hunter’s observation, which lead to the discovery of Hurler and Hunter Syndrome. In 1968, the diseases were considered to be identical. Also, in the same year, the Hunter Syndrome was regarded as a milder variant of the Hurler syndrome. In 1978, Lorincz published a book distinguishing the two maladies as distinct conditions. In 1968, it was hypothesised that the disorders were caused by inadequate mucopolysaccharide breakdown.

Seven distinct clinical categories and numerous subtypes of mucopolysaccharidoses have been identified at present. Despite the fact that each case of M.P.S. is clinically unique, the majority of patients experience a period of normal development followed by a decline in physical or mental function. Individuals may exhibit cognitive deficits, developmental delays, or severe behavioural issues, depending on their M.P.S. type. Numerous individuals experience hearing loss, neurosensory impairment, or both. Unfortunately, there is no cure for these disorders; therefore, treatment focuses on enhancing the quality of life.

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Visit the M.P.S. Society website and submit an application for one of the numerous volunteer opportunities available in your area. Include your peers and family in the process. The greater the number, the happier!

Make contributions

Giving back to your community can be extremely beneficial! You can participate in the observance of M.P.S. Awareness Day by donating to organisations involved in M.P.S. advocacy and research.

Disseminate information via social media

Participate in the festivities by raising awareness on social media. Share M.P.S.-related information with the appropriate identifiers.

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Five Interesting Facts About Multiple Sclerosis

It is genetically inherited

M.P.S. is a genetic disorder that is inherited.

Its severity fluctuates

The severity of M.P.S. symptoms varies from person to person.


M.P.S. VII, also known as cunning syndrome, is the rarest form of M.P.S.

Urine test diagnosis

Mucopolysaccharidosis in the urine can be utilised to diagnose M.P.S.

Enzyme substitution therapy

M.P.S. is treated with enzyme replacement therapy to alleviate non-neurological discomfort and symptoms.


We enjoy caring

We care about those whose lives have been taken by M.P.S. M.P.S. On Awareness Day, those with M.P.S. disorder who have passed away over the years are remembered. We also stand with those currently afflicted with M.P.S.

Spreads Knowledge

M.P.S. The purpose of Awareness Day is to increase global awareness of the condition. It also encourages collaboration in M.P.S. research and education.

Builds Community

M.P.S. The M.P.S. awareness day establishes a community for friends and families whose loved ones suffer from the disease. Communities can share their experiences for mutual support and encouragement.


Year Date Day
2023 May 15 Monday
2024 May 15 Wednesday
2025 May 15 Thursday
2026 May 15 Friday
2027 May 15 Saturday