Venus Williams lost to fellow American Madison Keys, falling 6-2, 7-5 in the opening round of the National Bank Open.
The 43-year-old Williams, a seven-time Grand Slam champion, dropped to 2-4 in six career matches against the 28-year-old Keys.
The 16th-ranked Keys broke Williams twice in the first set. She recorded two more breaks in the second and held on for the win.
Keys, who also is playing with fellow American Jennifer Brady in the women’s doubles tournament, now faces Italian Jasmine Paolini in the round of 32.
Czech Republic’s Karolina Pliskova posted a 6-3, 6-7 (8), 6-2 win over China’s Lin Zhu in the opening round.
Pliskova, ranked No. 23 in the world, had 11 aces and seven double-faults. She converted five of 16 break points.
Zhu had two aces and eight double-faults. She broke on two of her three opportunities.
